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It should be remembered that the term "morphine" could be applied (with a very long list of possible properties) to several different things and it is also important to note that such applications are only meant to be descriptive. Morphine exists as two types:
Morphine as a whole: this is the only type in which parent drug is the active substance. It doesn't matter whether is morphine, codeine, or any other morphine derivatives except the pure drug (e.g. morphine hydrate or methadone). as HCl OXO (the latter also referred as HCl oxycodone) Morphine OXO was patented in 1939 and is used to treat patients who need higher morphine doses than can be achieved with morphine hydrate because of adverse reaction. One problem with HCl oxycodone is that it not easy to manufacture and it has a very high price.
It should also be noted that all the following drugs are referred to together as "morphine derivatives" even though all of them have somewhat different properties. The main difference between these two groups is that the HCl oxycodone acts via same mechanism as morphine is supposed to act i.e. mu2-receptor stimulation, but it is different enough from morphine that there is no reason to expect that it acts like morphine in terms of toxicity.
The following drugs all have some morphine side effects, but they do not have the same mechanism as that of morphine in the human body (i.e. there is not a mu2ΞΈ-receptor activation):
Moxifloxacin: mu2-receptor antagonism
Moxisoxazole: mu2-receptor antagonism
Ibuprofen: mu2-receptor antagonism
Ticlopidine (for pain associated with neuropathic pain): mu2-receptor antagonism
This leaves only methadone which has the exact opposite mechanism as that of morphine and behaves like it: mu2-receptor activation. Therefore, given this evidence, there is good reason to believe that "morphine" as a whole includes the entire morphine family. At same time, the definition of "morphine" must include all the drugs that share same basic principle of action.
Further reading A new survey commissioned by the Australian Medical Association and designed to gauge public views around the safety of medical marijuana is out, with a wide divergence on whether it should remain legal. According to the results, 80% of respondents support the medicinal classification of cannabis as a useful treatment, while an equally high proportion (82%) believe the government should be forced "to do something." A further 19% disagreed.
In contrast there was a much more divisive picture when it came to its recreational classification, where 74% strongly disagreed with a government ban and 35% strongly agreed with it. This represents a stark contrast to some of the previous polls on matter, where support for the recreational cannabis classification was well in excess of 80%.
This disparity is due to a huge shift in public opinion, which is now overwhelmingly in favour of the medicinal classification. There is also evidence of shifts in public opinion other categories of cannabis, including an indication that support for its use in all forms is now at its highest point in a decade.
The ACM/PHORP survey, conducted over course of April, was conducted by YouGov in conjunction with the Australian College of Physiotherapists and the Australian Society of Psychiatric Physicians. It was conducted using online interviews on behalf of the organisation.
"This survey reveals that public support for the medicinal classification of cannabis is rapidly rising, despite continued opposition to its use in recreational settings," said ACP president Dr Michael Gannon. "Despite decades of government propaganda and a complete lack of evidence, Australians are beginning to become open-minded. That should serve as a vindication of the government's original prohibition agenda."
According to the survey, government's stated reason for restricting the use of cannabis is as follows:
"Contrary to popular belief, the medicinal classification of cannabis is justified by legitimate medical reasons, the majority of which cannot be explained through its recreational classification".
The same message was conveyed by the Australian Medical Association (AMA), when they stated that "the most frequently cited grounds for reclassifying cannabis as a Schedule II substance are that it is unlikely to be medically beneficial and Strattera 25mg $68.62 - $1.14 Per pill
may have undesirable reinforcing or sedating effects".
Some commentators have said that this has been achieved through clever public relations, rather than evidence-based policy, as a recent poll revealed some 65% of Australians believe cannabis should remain illegal "whether the medicinal use of cannabis is lawful or not".
This is perhaps not surprising given that all drugs.
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